In this episode, Anthropic’s Nicholas Carlini joins Patrick Gray and James Wilson to talk about advancements in AI-driven vulnerability research and exploit development.

Nicholas’ talk at the recent [un]prompted conference demonstrated how Anthropic’s Opus 4.6 could find and exploit vulnerabilities in popular open source projects. In the short few weeks since then, Anthropic announced a new model that’s already identifying hundreds of bug fixes across critical software. Nicholas talks us through the work he does at Anthropic, what’s possible and the limitations with current frontier models, and where this goes from here.